嘌呤核苷磷酸化酶在生物体内广泛存在。它可以将核苷分解为碱基和戊糖-1-磷酸,该反应是可逆的。嘌呤核苷磷酸化酶在嘌呤核苷酸补救合成代谢中十分重要,在人体中嘌呤核苷磷酸化酶的缺乏会导致T细胞功能的损伤。
Appearance: White powder, lyophilized
Source: Microorganism
Enzyme Commission Number: EC 2.4.2.1
CAS Number: 9030-21-1
Storage temperature: -20℃
Specific activity: ≥ 200U/mg protein
Unit definition: One unit will cause the phosphorolysis of one micromole of inosine to hypoxanthine and ribose 1-phosphate per min at pH 7.7 at 37℃.
PROPERTIES
Molecular weight 32 kDa (SDS-PAGE)
Isoelectric point 6.0
Optimum pH: 7.5~ 8.0
Optimum temperature: 60℃
pH Stability 5.0~10.0(30℃,16hr)
Thermal stability < 55℃ (pH 7.7, 30min)