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Myxochelin A

来源：作者：人气：-发表时间：2025-03-05 14:56:00【大中小】

Myxochelin A

人强效5-脂氧合酶抑制剂（5-LO），该酶催化花生四烯酸转化成白三烯的前两部，是众所周知的炎症和过敏反应介质。

铁离子螯合物

抗癌症抗生素，在体外抑制肿瘤细胞侵袭。

抗菌化合物

具有清除自由基活性的抗氧化剂。

产品列表

产品编号	产品名称	产品规格
AG-CN2-0470-C100	Myxochelin A 粘液素A	100 μg
AG-CN2-0470-M001	Myxochelin A 粘液素A	1 mg

参考文献

[1] Myxochelin A, a new iron-chelating compound from Angiococcus disciformis (Myxobacterales). Production, isolation, physico-chemical and biological properties: B. Kunze, et al.; J. Antibiot. 42, 14 (1989)

[2] Myxochelin A, a cytotoxic antibiotic from the myxobacterium Angiococcus disciformis: J.W. Ahn, et al.; OPEM 2, 64 (2001)

[3] Antioxidative and free radical scavenging activities of Myxochelin A isolated from Angiococcus sp.(Myxobacteria): H.-H. Lee, et al.; Food Sci. Biotech. 11, 184 (2002)

[4] Absolute configuration and antitumor activity of myxochelin A produced by Nonomuraea pusilla TP-A0861: S. Miyanaga, et al.; J. Antibiot. 59, 698 (2006)

[5] Synthesis and evaluation of myxochelin analogues as antimetastatic agents: S. Miyanaga, et al.; Bioorg. Med. Chem. 17, 2724 (2009)

[6] Myxochelins target human 5-lipoxygenase: S. Schieferdecker, et al.; J. Nat. Prod. 78, 335 (2015)

[7] Harnessing enzymatic promiscuity in Myxochelin biosynthesis for the production of 5-Lipoxygenase inhibitors: J. Korp, et al.; Chembiochem. 16, 2445 (2015)