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Ganglioside sugars (Ganglio-Series) 神经节苷脂糖 - Elicityl细菌发酵生产低聚葡聚糖产品 (6)

来源:作者:人气:-发表时间:2015-01-22 13:15:00【
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Glycan Oligosaccharides 细菌发酵生产的葡寡糖(低聚葡聚糖)
Ganglioside sugars (Ganglio-Series) 神经节苷脂糖
神经节苷脂是复杂的鞘糖脂(简称GSL,也被称为糖脂),包含唾液酸。它们是脊椎动物细胞膜的建构单元, 在细胞到细胞和细胞到细胞外基质(毒素,激素,病毒的受体……)通信时发挥关键作用。 作为肿瘤发病机制的一部分,这些分子算是疫苗的进攻目标。

神经节苷脂糖系统命名法:
G代表神经节苷脂
M, D, T & Q分别代表单个,两个,三个,四个唾液酸
1,2,3为薄层色谱中距离迁移的顺序


了解更多
Modified from Essentials of Glycobiology 2nd Edition, Varki A, Cummings RD, Esko JD, et al., editors. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
J. Heimburg-Molinaro et al., Vaccine 29 (2011) 8802-8826.
S. Hakomori. Biochimica etBiophysica Acta 1780 (2008) 325-346.
上海西宝生物提供神经节苷脂糖,原装进口,咨询/订购热线:400-021-8158
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规格: 5 mg, 25 mg, 100 mg, 1 g, 5 g
GLY090 GM3神经节苷脂糖/ 3'-唾液酸乳糖
GM3 Ganglioside sugar
3'Sialyllactose
Neu5Acα2-3Galβ1-4Glc
C23H38NO19Na FW 655.53
[35890-38-1]
 
GLY090
Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr 20, 699-722
Product provided for the following study: “Chemoenzymatic synthesis of GM3 and GM2 gangliosides containing a truncated ceramide functionalized for glycoconjugate synthesis and solid phase applications”. Jacques S et al,. 2006. Org Biomol Chem. 2006 Jan 7;4(1):142-54
GLY091 GD3神经节苷脂糖/ 二唾液酸乳糖
GD3 Ganglioside sugar
Disialyl lactose / DS-L
Neu5Acα2-8Neu5Acα2-3Galβ1-4Glc C34H54N2O27Na2 FW 968.76
 
GLY091
Tumor-associated carbohydrate antigen (TACA) Birkle S et al. 2003. Biochimie. 85(3-4): 455-63
Bovine Milk & Colostrum P. K. Gopal et al. British Journal of Nutrition (2000), 84, Suppl 1, S69-S74
GLY092 GT3神经节苷脂糖/ 三唾液酸乳糖
GT3 Ganglioside sugar
Trisialyl lactose
Neu5Acα2-8Neu5Acβ2-8Neu5Acα2-3Galβ1-4Glc
C45H70N3O35Na3 FW 1282.00
GLY092
GLY105 GQ3神经节苷脂糖/ 四唾液酸乳糖
GQ3 Ganglioside sugar
Quadrisialyl lactose
Neu5Acα2-8Neu5Acα2-8Neu5Acβ2-8Neu5Acα2-3Galβ1-4Glc
C56H86N4O43Na4 FW 1595.23
GLY105
GLY093 GM2神经节苷脂糖
GM2 Ganglioside sugar
GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C31H51N2O24Na FW 858.72
GLY093
GLY094 GD2神经节苷脂糖
GD2 Ganglioside sugar
GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc
C42H67N3O32 Na2 FW 1171.95
GLY094
GLY095 GT2神经节苷脂糖
GT2 Ganglioside sugar
GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc
C53H83N4O40 Na3 FW 1485.19
GLY095
GLY096 GM1a神经节苷脂糖
GM1a Ganglioside sugar
Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc C37H61N2O29 Na FW 1020.86
[67063-78-9]
GLY096
GLY097 GM1b神经节苷脂糖
GM1b Ganglioside sugar
Neu5Acα2-3Galβ1-3GalNAcβ1-4Galβ1-4Glc
C37H61N2O29Na FW 1020.86
GLY097
GLY098 GD1a神经节苷脂糖
GD1a Ganglioside sugar
Neu5Acα2-3Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc
C48H77N3O37Na2 FW 1334.09
GLY098
Functional ligands for myelin stability and the control of nerve regeneration Vyas, A et al., 2001. Biochimie. 83(7): 677-82.
GLY099 GD1b神经节苷脂糖
GD1b Ganglioside sugar
Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc
C48H77N3O37Na2 FW 1334.09
GLY099
GLY100 GT1a神经节苷脂糖
GT1a Ganglioside sugar
Neu5Acα2-8Neu5Acα2-3Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc
C59H93N4O45Na3 FW 1647.33
GLY100
GLY101 GT1c神经节苷脂糖
GT1c Ganglioside sugar
Galβ1-3GalNAcβ1-4(Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3)Galβ1-4Glc
C59H93N4O45Na3 FW 1647.33
GLY101
GLY102 aGM1(缺唾液酸GM1)神经节苷脂糖 / GA1
aGM1 (asialo GM1) Ganglioside sugar / GA1
Galβ1-3GalNAcβ1-4Galβ1-4Glc
C26H45NO21 FW 707.62
[75645-24-8]
GLY102
GLY103 岩藻糖GM1神经节苷脂糖
Fucosyl GM1 Ganglioside sugar
Fucα1-2Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc
C43H71N2O33Na FW 1168.00
GLY103
Tumor associated carbohydrate antigen expressed in small cell lung cancer (TACA), Dickler. MN et al,. Clin Cancer Res. 1999. Oct ; 5(10): 2773-9
GLY104 aGM2(缺唾液酸GM2)神经节苷脂糖 / GA2
aGM2 (asialo GM2) Ganglioside sugar / GA2
GalNAcβ1-4Galβ1-4Glc
C20H35NO16 FW 545.48
GLY104
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