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胃蛋白酶原II(PGII)-磁微粒化学发光法(AE/<font color='red'>AP</font>)/荧光免疫层析解决方案(含保护剂评估)
PG是胃蛋白酶的无活性前体,可分为PGI和PGII种亚型。PGII除由胃底腺分泌外,胃窦幽门腺和近端十二指肠 Brunner腺亦可分泌。当胃黏膜发生萎缩时,血清PGI水平和(或)PGI/II比值(PGR)降低。[查看]
http://cxbio.com/Article/PGII_1.html
抗磷酸化Tau S422,单克隆抗体(<font color='red'>AP</font>422)
Tau是微管结合蛋白的一种,主要在中枢神经系的神经细胞中表达,维持微管的稳定。有报道指出,在阿尔茨海默病患者的脑中,积蓄了磷酸化Tau的神经纤维发生变化,其变化程度与痴呆症的病重程度相关。因此,为了研究阿尔茨海默病的原因以及开发其药物,Tau被广泛研究。FUJIFILM Wako推出了各种Tau抗体、磷酸化Tau S422抗体就是其中之一。[查看]
http://cxbio.com/Article/Tau_S422_1.html
聚谷氨酰化修饰单抗(GT335)(生物素标记)
聚谷氨酰化(polyglutamylation)是一种可逆的翻译后修饰(PTM),通过酶与谷氨酸残基上γ位的羧基作用修饰蛋白。该作用产生大量负电荷,以此调节微管蛋白和其他蛋白间,包括微管结合蛋白(MAPs)和分子马达间相互作用,维持微管蛋白的稳定。[查看]
http://cxbio.com/Article/anti-Polyglutamylation_1.html
Cell子刊:2种中心体相关蛋白质不为人知的新功能
在一项新的研究中,耶鲁大学的研究人员发现了两种在这种调节中发挥作用的蛋白质,PPP2R3C,MAP3K1,从而揭示了中心体相关疾病,并揭示了潜在的治疗目标。[查看]
http://cxbio.com/Article/cellzk2zzxtxgdbzbwrz_1.html
Seebio(R) 高活性重组碱性磷酸酶(ALP)
碱性磷酸酶(Alkaline Phosphatase ,AP)是一种膜结合糖蛋白。与辣根过氧化物酶(HRP)相比,碱性磷酸酶具有稳定性和高敏感性的优势。AP在生物学尤其是分子生物学和免疫学领域有着广泛的应用。[查看]
http://cxbio.com/Article/Re-alp_1.html
25-羟基维生素D-磁微粒化学发光法(AE/<font color='red'>AP</font>) /荧光免疫层析解决方案(双抗体夹心法)
在医学上,对血液中25-羟基维生素D的检测经常被用于确定体内维生素D的含量,血液中25-羟基维生素D的浓度被认为是体现人体维生素D状态的优异指标。针对25-羟基维生素D抗原的检测(夹心法),西宝生物推出2种抗体及3种解离剂。25-羟基维生素D抗体(货号:ECY4531B)识别抗原抗体复合物;25-羟基维生素D抗体(货号:ECY4531C)识别小分子抗原。[查看]
http://cxbio.com/Article/25-OH-VD-TEST_1.html
载脂蛋白E ELISA 试剂盒 ApoE ELISA kit
高灵敏度载脂蛋白E ELISA 试剂盒可在3.5h内检测血清、血浆、细胞培养物上清和组织匀浆中的载脂蛋白E。[查看]
http://cxbio.com/Article/ApoE_ELISA_1.html
幽门螺杆菌(HP.CagA)-磁微粒化学发光法(AE/<font color='red'>AP</font>)解决方案
西宝生物开发的高质量幽门螺旋杆菌(CagA)重组抗原,可应用于体外诊断幽门螺杆菌抗体IgG/IgM检测试剂盒开发,适用于化学发光等多种应用场景,助力肠道研究防控无“幽”。[查看]
http://cxbio.com/Article/hp_CagA_AEAP_1.html
Nature子刊:两种调节线粒体自噬的蛋白质,开辟了一条新的途径
WEHI的研究人员与维也纳大学的一个团队合作,发现了两种调节线粒体自噬的蛋白质, NAP1和SINTBAD,它们参与调节细胞中有丝分裂的激活。[查看]
http://cxbio.com/Article/20240725_industrialnews_1.html
VLVbio 细胞凋亡坏死检测试剂盒
VLVbio,专注于研究检测细胞死亡方式(凋亡或坏死),可提供M30 Apoptosense? ELISA试剂盒和M65 EpiDeath? ELISA试剂盒,广泛用于非酒精性脂肪性肝炎(NASH) 的研究和药物开发领域。[查看]
http://cxbio.com/Article/VLVbio_1.html
细胞凋亡M30 Apoptosense(R) ELISA试剂盒
M30 Apoptosense(R) ELISA 是 PEVIVA 的畅销产品。可用于定量检测表达角蛋白18(K18)细胞(人)的凋亡情况。检测结果可信度高,检测结果重复性好。[查看]
http://cxbio.com/Article/M30_Apoptosense_1.html
细胞死亡 M65(R) ELISA 试剂盒 M65(R) ELISA
M65(R) ELISA 检测来自死亡细胞释放的可溶性角蛋白18(K18),可以整体评估细胞的死亡情况,判断是由于细胞凋亡还是细胞坏死引起的细胞死亡。M65(R) ELISA 最初是为了和 M30 Apoptosense(R) ELISA 配套使用而设计研发的,后者特异性检测细胞凋亡。两者配套使用,可定量检测总的细胞死亡、细胞凋亡和细胞坏死。[查看]
http://cxbio.com/Article/M65ELISA_1.html
胃蛋白酶原I(PGI)-磁微粒化学发光法(AE/<font color='red'>AP</font>) /荧光免疫层析解决方案
PG是胃蛋白酶的无活性前体,可分为PGI和PGII种亚型。PGI主要由胃体和胃底腺的主细胞和颈黏液细胞分泌,而 PGII除由胃底腺分泌外,胃窦幽门腺和近端十二指肠 Brunner腺亦可分泌。当胃黏膜发生萎缩时,血清PGI水平和(或)PGI/II比值(PGR)降低。血清中约存在人体1%的PG,其血清水平可作为胃黏膜形态和功能状态的标志,联合Hp检测可识别出胃癌的高危个体。[查看]
http://cxbio.com/Article/PGI_test_1.html
药物性肝损伤
药物性肝损伤(DILI)是急性肝功能衰竭的常见的原因之一,可能需要进行肝移植,在某些情况下甚至会出现致命后果。由于目前市场上现有药物具有的毒性,导致DILI对新药的研发和临床都有很大影响。使用M30 Aptosense? ELISA检测的循环ccK18水平优于血清ALT活性。通过M65 EpiDeath? ELISA试剂盒检测的K18水平在检测对乙酰氨基酚给药方面,比标准肝脏标志物更为灵敏。[查看]
http://cxbio.com/Article/DILI_1.html
NASH生物标记物检测试剂盒
M30 Apoptosense(R) ELISA可检测 K18 片段的浓度,是检测和筛查 NASH 的可靠的特异性工具。最近的两项荟萃分析表明,K18 片段的水平可以预测 NASH 的存在,其 pooled AUROC 值为 0.82、伴随 78% 的灵敏度和 86% 的特异性;AUROC 值为 0.8445、伴随 83% 的灵敏度和 71% 的特异性。[查看]
http://cxbio.com/Article/M30_1.html
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