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昆虫细胞培养用培养基 - PSFM-J1 液体培养基
PSFM-J1 液体培养基,是昆虫细胞 Sf9、High Five(H5)培养用的无血清培养基。[查看]
http://cxbio.com/Article/PSFM-J1_1.html
抗BIF1单克隆抗体(克隆号:BIF1-443)
野生型(left lane)和 Bif-1 缺陷型(right lane)小鼠胚胎成纤维细胞在使用抗 Bif-1 抗体(克隆号:BIF1-443)所得结果,抗体按1:500稀释,并用含有3%脱脂牛奶的 TBS-T 溶液进行封闭处理。预测条带大小为 42 kDa 左右[查看]
http://cxbio.com/Article/Anti-BIF1_1.html
肺癌脑转移的新机制
2023年8月17日,广州医科大学何建行及克利夫兰诊所鲍仕登共同通讯在Cancer Cell 在线发表题为“CD44+ lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration”的研究论文,该研究表明报道了肺腺癌(ADC)中来自CD44+肺癌干细胞(CSCs)的血管周细胞通过G蛋白偶联受体124 (GPR124)增强的跨内皮迁移(TEM)引起肿瘤脑转移。[查看]
http://cxbio.com/Article/fanzydxjz_1.html
Nature Medicine发现了新的基因变异,可以预防阿尔茨海默病
通过由哥伦比亚安蒂奥基亚大学的研究人员领导的临床评估,在Mass Eye and Ear和洛杉矶儿童医院进行的遗传和分子研究,在MGH进行的神经成像和生物标志物研究,以及由德国汉堡-埃本多夫大学医学中心的研究人员进行的神经病理学研究,研究小组确定了一种新的基因变异,可以预防阿尔茨海默病。该变异发生在与2019年报道的同一家族病例不同的基因上,但指出了一种共同的疾病途径。他们的发现还指出了大脑的一个区域,这个区域可能在未来提供最佳的治疗目标。[查看]
http://cxbio.com/Article/naturemedicinefxlxdj_1.html
献血可以解毒!JAMA子刊:定期献血可有效减少血液中难以去除的有害氟化物
近日,一篇题为“Effect of Plasma and Blood Donations on Levels of Perfluoroalkyl and Polyfluoroalkyl Substances in Firefighters in Australia”的研究发表于JAMA Network Open。本次研究由澳大利亚科学家Robin Gasiorowski博士及其团队主导,这项随机试验发现定期献血或献血浆可显著降低血液中PFAS水平,其中,献血浆更有效。[查看]
http://cxbio.com/Article/xxkyjdjamazkdqxxkyxj_1.html
打破固有认知!Science揭秘肠道运行新机制:合成胆固醇中的“好学生”,或为肝脏疾病治疗带来新靶点
近日,华盛顿大学医学院的研究团队在Science 发表最新研究 Enterically derived high-density lipoprotein restrains liver injury through the portal vein,该项研究指出,人体的肝脏承担了在血液中产生与合成大部分高密度脂蛋白的角色,但类似的合成也发生在肠道。研究人员在小肠内发现了一种特殊类型的高密度脂蛋白HDL3,它以HDL的亚种形式存在,会与肠道内的脂多糖炎症分子结合,阻断引起肝脏炎症的细菌信号,以达到保护肝脏的目的。[查看]
http://cxbio.com/Article/dpgyrzsciencejmcdyxx_1.html
Nature 三连重磅!识破癌细胞的“诡计”,为结直肠癌患者带来新希望
近日, 顶级学术期刊《Nature》三连发表重磅文章拆穿了癌细胞的“把戏”,为结肠癌高危人群提供了新的预防策略。同时,《Nature》还在线发表题为Cancer stem cells in the gut have a bad influence on neighbouringcells的 News & Views,提供了有关癌细胞及其邻近细胞在肠道中的竞争动态的重要见解。[查看]
http://cxbio.com/Article/natureslzbspaxbdgjwj_1.html
北大科学家发Cell顶刊:通过剪接体抑制剂可使小鼠产生全能干细胞
近日,北京大学的研究人员在《Cell》杂志上在线发表了题为“Mouse totipotent stem cells captured and maintained throughspliceosomal repression”的文章,发现剪接体抑制能够产生小鼠全能干细胞。[查看]
http://cxbio.com/Article/bdkxjfcelldktgjjtyzj_1.html
JAMA:糖尿病发病年龄越小,患痴呆症的风险越高
2021年4月27日,法国巴黎大学Archana Singh-Manoux团队在《美国医学会杂志》发表了研究成果,题为“Association Between Age at Diabetes Onset and Subsequent Risk of Dementia”,研究了糖尿病发病年龄与痴呆风险的相关性。[查看]
http://cxbio.com/Article/jamatnbfbnlyxhcdzdfx_1.html
癌症免疫疗法副作用不容忽视,不仅要“治”,还要会“防”
近日,麻省总医院(MGH)的研究人员在《癌症免疫治疗杂志》上发表了一篇文章,深入分析了接受癌症免疫疗法治疗后的患者出现免疫相关不良事件(irAE)的发生概率。[查看]
http://cxbio.com/Article/azmylffzybrhsbjyzhyh_1.html
Cell子刊:孕妇肥胖会影响孩子的认知和社交能力障碍!高纤维饮食或能改善恢复!
近日,来自西北农林科技大学和上海交通大学的研究人员在《Cell Metabolism》上发表了题为High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis的研究成果,发现肠道微生物菌群-代谢物-脑轴可能是孕产妇肥胖引起后代认知和社交能力缺陷的基础,而摄入较高的膳食纤维可能是一种有潜力的干预措施。[查看]
http://cxbio.com/Article/cellzkyffphyxhzdrzhs_1.html
糖尿病患者的福音来了!《BMC》发文:NCAS可作为饮食糖替代品
近日,《BMC》发布了一篇题为High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice的文章,发现人和小鼠短期内食用糖精量在最大可接受水平(ADI)时,不会改变其肠道菌群稳态或引起葡萄糖耐受不良。[查看]
http://cxbio.com/Article/tnbhzdfyllbmcfwncask_1.html
Nature子刊:揭示“颜值”背后的遗传信息
早期发育过程中胎儿的面部结构往往会融合在一起,那么,后来的发育过程中我们的面部是如何形成,形态结构又是如何随进化而发生改变的呢?近日,来自美国宾夕法尼亚州立大学的研究人员在《Nature Genetics》上发表了题为Insights into the genetic architecture of the human face的研究成果,使用多变量全基因组关联研究,对8246例个体进行了荟萃分析,从中确定了203个与正常范围的面部变异相关的单核苷酸多态性(SNP),为了解个体的遗传如何协调塑造复杂的形态特征提供了一定的见解。[查看]
http://cxbio.com/Article/naturezkjsyzbhdycxx_1.html
Cell子刊:人类能否战胜糖尿病?这方面可能要向猪学学了!
近日,国际一流学术期刊《Cell Metabolism》在线发表了上海交通大学附属第六人民医院贾伟教授团队名为“Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism”的研究,揭示猪不易患糖尿病的背后机制:猪胆酸通过不同的TGR5和FXR信号机制来改善葡萄糖稳态。[查看]
http://cxbio.com/Article/cellzkrlnfzstnbzfmkn_1.html
Cell解读!科学家开发出能观察和控制大脑神经活性的新工具!
日前,一项刊登在国际杂志Cell上题为“A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion”的研究报告中,来自斯坦福大学等机构的科学家们通过研究开发了一种新型分子探针,其或能帮助揭示大脑思考和记忆的分子机制,这种名为“flicker”(Fast Light and Calcium-Regulated Expression<快速光和钙调节表达技术>或FLiCRE)的工具或能用于在任何细胞内执行各种研究任务,包括标记、记录和控制细胞功能等。[查看]
http://cxbio.com/Article/celljdkxjkfcngchkzdn_1.html
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蛋白保护剂GH
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Bandwidth Standard Toluene in Hexane - Ratio of 268.7nm peak to 266.8nm trough
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Stray Light Inorganic Cut-off filter (390nm)Sodium Nitrite
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Stray Light Inorganic Cut-off filter (205nm)Sodium Chloride
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Stray Light Inorganic Cut-off filter (200nm)-Potassium chloride
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Bandwidth Standard Blank - Ratio of 268.7nm peak to 266.8nm trough
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Stray Light Blank Aqueous
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High Concentration Multi-Element Linearity Standard
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Standards low, medium and high concetrations
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Polychlorinated Biphenyls in Insulation Oil (High Concentrations)
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Fine Alumina Powder for Fine Ceramics-High Purity
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Acid Content High Acid Range 3.0M to 10M
Acid Content High Acid Range 3.0M to 10M
Brix High Sucrose (Brix) Range 35% to 60%
Brix High Sucrose (Brix) Range 35% to 60%
Chloride Content High Chloride Range 2.0M to 4.0M
Chloride Content High Chloride Range 2.0M to 4.0M
Conductivity High Conductivity Range 100,000uS/cm to 500,000uS/cm
Conductivity High Conductivity Range 100,000uS/cm to 500,000uS/cm
Density @ 20℃ High Density Range 1.ug/mL to 2.ug/mL
Density @ 20℃ High Density Range 1.ug/mL to 2.ug/mL
Osmolality High Osmolality Range 1,000mOsm/kg to 3,000mOsm/kg
Osmolality High Osmolality Range 1,000mOsm/kg to 3,000mOsm/kg
High Range pH @ 20℃ pH range 8.1 to 11
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High Range pH @ 25℃ pH range 8.1 to 11
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苯并 (ghi) 苝
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