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Nature子刊新研究为癌症如何破坏干细胞精心调整的表观过程提供了新见解 [行业新闻]

: 在皮肤中，一些异常的成年表皮干细胞后来会开启SOX9。现在洛克菲勒的研究人员已经揭示了这一恶性转变背后的机制。事实证明，SOX9属于一类特殊的蛋白质，它控制着遗传信息从DNA到mRNA的传递。这意味着它有能力撬开密封的遗传物质口袋，与之前沉默的基因结合，并激活它们。他们的研究结果发表在《自然细胞生物学》杂志上。[查看]; http://cxbio.com/Article/20230802_1.html

有木有增加蛋白表达量的转染试剂？ ——试试Seebio?小西家的阳离子聚合物PEI [SEEBIO]

: 聚乙烯亚胺（Polyethylenimine，PEI）作为化学转染的新宠，近年来倍受关注，无论是科研还是在工业化、大规模瞬时转染表达重组蛋白或病毒载体领域都是使用广泛的转染试剂。西宝生物开发的新一代阳离子聚合物产品着重优化和DNA结合能力。为了更好的了解PEI这款阳离子聚合物产品[查看]; http://cxbio.com/Article/PEI-transfecting_1.html

Nature解开一种蛋白质，研发一种新的生物技术工具 [行业新闻]

: 科学家们已经揭开了Argonaute蛋白的逐步激活过程，这种蛋白质在生命的所有领域都有着深刻的进化历史，为利用其功能作为生物技术工具打开了大门。[查看]; http://cxbio.com/Article/naturejkyzdbzyfyzxds_1.html

《PNAS》从过度反应蛋白合成到认知障碍，敲除1个基因即可 [行业新闻]

: 日本理研研究所的研究人员发现了蛋白质合成与神经发育障碍之间的联系，发现蛋白质生产过程中过度活跃的质量控制过程会抑制神经生长和交流，导致认知功能障碍。这为治疗这类疾病开辟了潜在的新途径。[查看]; http://cxbio.com/Article/20230727_1.html

西宝生物技术服务项目 [SEEBIO]

: 西宝生物已建立蛋白进化及表达、PEG及其衍生物、诊断试剂开发、合成生物学等技术应用平台，基于强大的研究技术团队，我们可以为客户提供多种生物实验外包服务，包括重组蛋白表达纯化类服务、分子/免疫学检测类服务、mRNA制备与递送及整体项目技术服务。[查看]; http://cxbio.com/Article/xbswjsfwxm_1.html

“瑞士军刀”转录因子不仅能结合DNA和蛋白质，还能结合RNA [行业新闻]

: 在7月3日发表在《Molecular Cell》杂志上的一篇论文中，Young和怀特黑德研究所的博士后Ozgur Oksuz和Jonathan Henninger揭示，除了DNA和蛋白质，许多转录因子也可以结合RNA。研究人员发现，RNA结合使转录因子在DNA结合位点附近停留的时间更长，有助于微调基因表达。这种对转录因子如何工作的重新思考可能会导致对基因调控的更好理解，并可能为基于RNA的治疗提供新的靶点。[查看]; http://cxbio.com/Article/tfsinteractwithRNA_1.html

Nature证明“生命自有出路”：最小细胞的进化 [行业新闻]

: Lennon的研究小组一直在研究一种人工合成的最小细胞，这种细胞除了基本基因外，其他所有基因都被剥离了。研究小组发现，这种简化版细胞的进化速度和正常细胞一样快——这证明了生物体的适应能力，即使是一个看似没有什么灵活性的非自然基因组。[查看]; http://cxbio.com/Article/naturezmsmzyclzxxbdj_1.html

聚茴脑磺酸钠 - 血培养试剂 [SEEBIO]

: 聚茴脑磺酸钠（Sodium Polyanethole Sulfonate，SPS，CAS 55963-78-5），是白色至淡黄色结晶体或粉末。聚茴香脑磺酸钠（SPS）可以中和血液里的微量抗生素，提高血培养的阳性率，用于血培养里的厌氧瓶或双向培养瓶。[查看]; http://cxbio.com/Article/jhnhsnxpysj_1.html

PNAS新研究：致病菌利用肠道黏液层中的一种糖来感染肠道 [行业新闻]

: 发表在《美国国家科学院院刊》(PNAS)上的研究结果表明，肠道细菌感染和一系列与肠道细菌有关的慢性疾病，包括炎症性肠病(IBD)、乳糜泻、肠易激综合征和短肠综合征，都有可能成为治疗目标。[查看]; http://cxbio.com/Article/pnasSialicacid_1.html

阿尔兹海默症早期诊断标志物 [SEEBIO]

: 阿尔兹海默症的检测主要有：影像学检查、脑脊液检测、神经心理学测验、脑电图检查。 AD早期诊断的生物标志物：Aβ42、Аβ42/ Aβ40、APPr、Aβ寡聚体、T-tau、P-tau、AD7c-NTP、NFL、VLP-1、hFABP、TGF-?、YKL-40、PGE2、IsoPs、miRNA-342-3p、Ferritin、Pb4等[查看]; http://cxbio.com/Article/aezhmzzqzdbzw_1.html

西宝生物诚邀您参加2023 analytica China慕尼黑上海分析生化展 [热点活动]

: 在这个充满热情与浪漫的7月，第十一届中国国际分析、生化技术、诊断和实验室技术博览会暨analytica China将于2023年7月11日-13日在上海国家会展中心举行。西宝生物团队真诚相邀，静候您到现场莅临与指导。这个七月，等花开，等蝉鸣，等你来。慕尼黑上海分析生化展（analytica China）已成为分析和生化技术领域高质量的国际会议，聚焦行业快速发展，推动行业技术创新进步。[查看]; http://cxbio.com/Article/analytica2023_1.html

Nature Methods：研究复杂基因组相互作用 [行业新闻]

: 马克斯·德尔布赖克中心柏林医学系统生物学研究所(MDC-BIMSB)的研究人员已经开发出一种名为基因组结构测绘(GAM)的技术，可以窥视基因组，并以绚丽的彩色看到它。Pombo实验室在Nature Methods上发表的一项新研究报告称，GAM揭示了基因组空间结构的信息，而这些信息对于仅使用Hi-C(2009年开发的用于研究DNA相互作用的主要工具)的科学家来说是不可见的。[查看]; http://cxbio.com/Article/naturemethodsyjfzjyz_1.html

是什么决定了CD8+ T细胞的命运？Immunity新研究指向cBAF复合物 [行业新闻]

: 最近，索尔克生物研究所Susan Kaech教授和Diana Hargreaves副教授领导的团队发现，一种名为cBAF的蛋白质复合物可通过“开门或关门”来控制T细胞的命运。这项研究成果于6月13日发表在《Immunity》杂志上，阐明了T细胞如何对抗和记忆感染，同时为开发更有效的疫苗和癌症治疗方法铺平了道路。[查看]; http://cxbio.com/Article/ssmjdlcd8txbdmyimmun_1.html

PNAS：基于CRISPR/cas9的基因驱动可以抑制农业害虫 [行业新闻]

: 北卡罗来纳州立大学研究人员已经开发出一种基于CRISPR/Cas9的“归巢基因驱动系统”，可以用来抑制斑翅果蝇 Drosophila suzukii 的数量。研究人员开发了双CRISPR基因驱动系统，针对一种特定的斑翅果蝇基因，这种基因被称为doublesex，对果蝇的性发育很重要。[查看]; http://cxbio.com/Article/pnasjycrisprcas9djyq_1.html

Cancer Cell革命性的新发现：癌症风险与环状RNA之间的重要联系 [行业新闻]

: 澳大利亚癌症研究人员在个人癌症风险与环状RNA的功能之间建立了重要的新联系，环状RNA是最近发现的存在于我们细胞中的基因片段家族。弗林德斯大学领导的一项新研究发表在癌症期刊《癌细胞》上，该研究发现，我们许多人体内的特定环状RNA可以附着在细胞中的DNA上，导致DNA突变，从而导致癌症。[查看]; http://cxbio.com/Article/cancercellgmxdxfxazf_1.html

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: N-亚硝基假木贼碱 (NAB)

: N-亚硝基新烟草碱 (NAT)

: (R,S)-N-亚硝基新烟草碱 (NAT) D4

: Analytical Volumetric Solution Hydrochloric Acid 0.01N(0.01M)

: Analytical Volumetric Solution HydroChoric Acid 0.1N 0.1M

: Analytical Volumetric Solution Hydrochloric Acid 1.0N 1.0M

: Analytical Volumetric Solution Iodine 0.01N 0.005M

: Analytical Volumetric Solution Iodine 0.01N 0.005M

: Analytical Volumetric Solution Iodine 0.01M 0.02N

: Analytical Volumetric Solution Iodine 0.01M 0.02N

: Analytical Volumetric Solution Potassium Hydroxide 0.1N 0.1M

: Analytical Volumetric Solution Potassium Hydroxide 1.0N 1.0M

: Potassium thiocyanate solution 20% w/v

: Potassium thiocyanate solution 5% w/v

: Analytical Volumetric Solution Sodium Hydroxide 10N (10M)

: Analytical Volumetric Solution Sodium Hydroxide 0.01N (0.01M)

: Analytical Volumetric Solution Sodium Hydroxide 0.02N 0.02M

: Analytical Volumetric Solution Sodium Hydroxide 0.1N 0.1M

: Analytical Volumetric Solution Sodium Hydroxide 0.1N 0.1M

: Analytical Volumetric Solution Sodium Hydroxide 0.25N 0.25M

: Analytical Volumetric Solution Sodium Hydroxide 0.35465N 0.35465M

: Analytical Volumetric Solution Sodium Hydroxide 0.5N 0.5M

: Sodium Carbonate 20%

: Analytical Volumetric Solution Sodium Thiosulphate 0.05N 0.05M

: Analytical Volumetric Solution Sodium Thiosulphate 0.0551N 0.0551M

: Analytical Volumetric Solution Sodium Thiosulphate 0.1N 0.1M

: TISAB for wine analysis (Dir. 2676/90) for the fluoride determination by selective electrodes.

: Phosphatase Test Carbonate Bi-Carbonate Buffer (Aschafenburg and Mullen Phosphatase test Buffer)

: Potassium Permanganate , 5% w/v

: Sodium Hydroxide, NaOH, 2% w/v

: 酸性橙6 NaCl ( 工业级)

: Analytical Volumetric Solution Calcium chloride 0.02N 0.01M

: Analytical Volumetric Solution Hydrochloric Acid 6.0N 6.0M

: Mehlich #3 Final Extraction Reagent

: CSK标准溶液硅酸盐(含3.05%NaCl, S1:50.0ug atom/L)

: CSK标准溶液硅酸盐(含3.05%NaCl, Si:0.0ug atom/L)

: CSK标准溶液硅酸盐(含3.05%NaCl,Si:100ug atom/L)

: CSK标准溶液硝酸盐(含3.05%NaCl,N:20.00ug atom/L)

: CSK标准溶液硅酸盐(含3.05%NaCl, Si:10.0ug atom/L)

: CSK标准溶液硝酸盐(含3.05%NaCl,N:5.00ug atom/L)

: CSK标准溶液硅酸盐(含3.05%NaCl, Si:200ug atom/L)

: CSK栎准溶液硝酸盐(含3.05%NaCl, N:40.00ug atom/L)

: CSK标准溶液硅酸盐(含3.05%NaCl,. Si:5.0ug atom/L)

: CSK标准溶液硝酸盐(含3.05%NaCl, N:0.00ug atom/L)

: CSK标准溶液硝酸盐(含3.05%NaCl, N:10.00ug atom/L)

: 2,6-Toluene diisocyanate - Methoxyphenyl piperazinyl

: Hexamethylene diisocyanate -Methoxyphenyl piperazinyl

: Methylene bisphenyl isocyanate -Methoxyphenyl piperazinyl

: ProteinA胶体金颗粒

: ProteinA 包被板

: 3,5-二氯-2-羟基苯磺酸钠|54970-72-8|DHBS|Sodium 3,5-chloro-6-hydroxybenzenesulfonate

: MPT-NAG|149263-94-5|6-甲基-2-硫代吡啶-N-乙酰-β-D-葡萄糖苷

: PNP-NAG

: 果糖-1,6-二磷酸.3Na

: 葡萄糖-6-磷酸.2Na

: D-葡萄糖-6-磷酸.Na

: EDTA-Na2; 乙二胺四乙酸二钠二水合物

: EDTA-Na4; 乙二胺四乙酸四钠盐二水合物

: Zwittergent 3-14,zwitterionic detergent, powder, N-Tetradecyl-N,N-dimethyl-3-ammonio-1-propane-sulfonate

: N-羟乙基乙二胺-N,N',N'-三乙酸.3Na

: 3-[(3-Cholamidopropyl)dimethylammonio]-2-Hydroxy-1-Propane sulfonate

: 氧化型辅酶I|烟酰胺腺嘌呤二核苷酸|53-84-9| β-NAD

: Alkalophilic proteinase

: Creatinine deiminase

: D-Fructose dehydrogenase

: Formaldehyde dehydrogenase

: Glycerol-3-phosphate dehydrogenase

: Glucose-6-phosphate dehydrogenase

: Glucose-6-phosphate dehydrogenase

: Glucose dehydrogenase (NAD(P)-dependent)

: Glucose dehydrogenase (PQQ-dependent)

: Glutamate dehydrogenase(NADP dependent)

: Glutamate dehydrogenase (NAD dependent)

: Glutamate dehydrogenase (NADP dependent)

: Glycerol dehydrogenase

: Glycerol kinase

: Glycerol kinase

: D-3-Hydroxybutyrate dehydrogenase

: Hexokinase

: Lactate dehydrogenase

: D-Lactate dehydrogenase

: Leucine dehydrogenase

: Malate dehydrogenase

: Protocatechuate 3,4-dioxygenase

: Anti biotin monoclonal antibody

: 1,5-Anhydroglucitol-6-phosphate Dehydrogenase

: 3-alpha-Hydroxysteroid Dehydrogenase

: 12α-Hydroxysteroid Dehydrogenase

: 3-Hydroxybutyrate Dehydrogenase

: ADP-dependent Hexokinase

: ADP-dependent Hexokinase

: Diaphorase (NADH)

: Diaphorase (NADPH)

: Glucose-6-phosphate Dehydrogenase

: Glycerol Kinase

: Hexokinase

: Hexokinase

: NAD Synthetase

: Phosphofructokinase

: Sphingomyelinase

: Xanthine Dehydrogenase

: Creatine Kinase

: Lactate Dehydrogenase

: Adenosine Deaminase,from calf intestine, suspension

: Cholesterol Esterase,from Pseudomonas species, lyophilizate

: Cholesterol Esterase, chemically modified,from Pseudomonas species, lyophilizate

: Cholesterol Esterase,from Pseudomonas species, solution

: Creatinase,from microorganism, lyophilizate

: Creatininase,from microorganism, lyophilizate

: Creatinine Deaminase,from Corynebacterium lilium, lyophilizate

: Galactose 1-Dehydrogenase,from E.coli overproducer, lyophilizate

: Galactose 1-Dehydrogenase,from E.coli overproducer, suspension

: Galactose 1-Dehydrogenase,from Pseudomonas fluorescens, suspension

: Glucose-6-phosphate Dehydrogenase (G6P-DH),rom Leuconostoc mesenteroides, expressed in E. coli,lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH), chemically modified,from Leuconostoc mesenteroides, expressed in E. coli,lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, expressed in E. coli,solution

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, expressed in E. coli,reduced phosphate, lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, suspension

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from yeast, lyophilizate

: Glutamate Dehydrogenase (NAD(P)),from E.coli overproducer, lyophilizate

: Glutamate Dehydrogenase (NAD(P)),from beef liver, lyophilizate

: Glutamate Dehydrogenase (NAD(P)),from beef liver, chemically modified, lyophilizate

: Glutamate Dehydrogenase (NAD(P)),from beef liver, solution

: Glycerol Kinase (GK),from Bacillus stearothermophilus, lyophilizate

: Glycerol Kinase (GK),from Bacillus stearothermophilus, solution

: Glycerol Kinase (GK), concentrated,from Bacillus stearothermophilus, solution

: Glycerol-3-phosphate Dehydrogenase,from rabbit muscle, suspension

: Hexokinase (HK),from yeast overproducer, lyophilizate

: Hexokinase (HK), chemically modified,from yeast overproducer, lyophilizate

: Hexokinase (HK),from yeast overproducer, solution

: Hexokinase (HK),from yeast, lyophilizate

: L-Lactate Dehydrogenase (L-LDH),from pig muscle, for use of AST/GOT-Determination according to IFCC recommendations, lyophilizate

: L-Lactate Dehydrogenase (L-LDH), chemically modified,from pig muscle, for use of AST/GOT-Determination according to IFCC recommendations, solution

: L-Lactate Dehydrogenase (L-LDH),from pig muscle, suspension

: L-Lactate Dehydrogenase (L-LDH),chemically modified,from pig heart, lyophilizate

: L-Lactate Dehydrogenase (L-LDH),from pig heart, suspension

: L-Lactate Dehydrogenase (L-LDH)from rabbit muscle, suspension

: Lipoprotein Lipase,from Pseudomonas species, lyophilizate

: Lipoprotein Lipase, chemically modified,from Pseudomonas species, lyophilizate

: Malate Dehydrogenase,from pig heart, lyophilizate

: Malate Dehydrogenase, chemically modified,from pig heart, lyophilizate

: Malate Dehydrogenase, IFCC Quality,from pig heart, lyophilizate

: Malate Dehydrogenase, IFCC Quality,from pig heart, solution

: N-Methylhydantoinase (ATP-hydrolyzing),from Arthrobacter species, expressed in E. coli, lyophilizate

: NAD(P)H Dehydrogenase (quinone) (Diaphorase),from pig heart, suspension

: Phosphogluconate Dehydrogenase (decarboxylating),from yeast, lyophilizate

: 6-Phosphogluconolactonase,from Leuconostoc mesenteroides, lyophilizate

: Pyruvate Kinase,from Bacillus stearothermophilus, lyophilizate

: Pyruvate Kinase,from rabbit muscle, suspension

: Carboxypeptidase B, recombinant,from rat pancreas, expressed in Pichia pastoris, solution

: Endoproteinase Asp-N, Sequencing Grade,from a mutant of Pseudomonas fragi, lyophilizate

: Endoproteinase Glu-C,from Staphylococcus aureus V8, lyophilizate, salt-free

: Endoproteinase Glu-C, Sequencing Grade,from Staphylococcus aureus V8, lyophilizate

: Endoproteinase Lys-C,from Lysobacter enzymogenes, lyophilizate

: Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate

: Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution

: Pronase,from Streptomyces griseus, lyophilizate

: Trypsin, recombinant,from porcine pancreas, expressed in Pichia pastoris

: N-Acylmannosamine 1-dehydrogenase (NAMD-E)

: Creatinase (C2-AE)

: Creatinase (C2-AT)

: Creatininase (C1- E)

: L-Fucose dehydrogenase(FDH-E)*

: Glucose-6-phosphate dehydrogenase (GPD-M)

: Glutaminase (GLN)

: 3alpha-Hydroxysteroid dehydrogenase (3aHSD-E)

: Lactate dehydrogenase (LDH-P)

: Lactate dehydrogenase (LDH-R)

: Malate dehydrogenase (MDH-P)

: Tannase (TAH)

: Cholesterol dehydrogenase

: Glucose-6-Phosphate Dehydrogenase

: Glycerol Kinase 6495.

: Hexokinase

: Lactate Dehydrogenase

: Lactate Dehydrogenase

: Malate Dehydrogenase 1521.

: Glucose Dehydrogenase (NAD Dependent)

: Glucose-6-Phosphate Dehydrogenase

: Hexokinase

: Proteinase K

: Glycerol Kinase Amano2

: Cholesterol Dehydrogenase Amano 5

: Glucose Dehydrogenase Amano 2

: Lactate Dehydrogenase Amano 3

: Malate Dehydrogenase Amano 3

: 克拉维酸钾|61177-45-5|Clavulanate K

: Penicillinase

: Penicillinase Bulk Powder

: 3,5-二氯苯磺酸.2Na

: 3,5-二氯-2-羟基苯磺酸钠 | Sodium 3,5-chloro-6-hydroxybenzenesulfonate | 54970-72-8

: 异硫氰酸荧光素酯, 5-FITC 5-Isothiocyanato fluorescein, CAS号 3326-32-7

: NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐

: 1.10菲啰啉, 1,10-Phenanthroline monohydrate, 5144-89-8

: 无水1.10菲啰啉, 1,10-Phenanthroline, 66-71-7

: 玫瑰红酸钠, Sodium rhodizonate, 523-21-7

: 萘酚绿B,Naphthol Green B ,19381-50-1

: 蛋白A|Recombinant Protein A

: 蛋白A/G|Recombinant Protein A/G

: 蛋白L | Recombinant Protein L

: Mannan-binding lectin (human, MBL)

: Mannan-binding lectin (chicken, MBL)

: Mannan-binding lectin (rat, MBL)

: Mannan-binding lectin (horse/swine, MBL)

: FastDNA? Spin Kit for Soil

: Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate

: Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate

: Lactate 2-Monooxygenase (Lactateoxidase),from Pediococcus species, lyophilizate

: Recombinant Cholesterol Oxidase

: Glucose Oxidase Amano NA

: trans-2-Nonenal 2,4-Dinitrophenylhyd razone Standard

: CNA标准品

: TFNA-AM标准品

: TFNA标准品

: 2- (3-chlorophenoxy)propionamide

: Methylene dithiocyanate

: Oxpoconazole fumarate

: Quinonamid

: N-Nitrosoanatabine 2,4,5,6 D4， 10ng/ul 于丙酮

: Prynachlor，10ng/ul 于环己烷

: USP Solution Ammonium Carbonate TS Conforms to USP 34

: USP Solution Ammonium Carbonate TS Conforms to USP 34

: USP Solution Ammonium Thiocyanate TS Conforms to USP 34

: USP Solution Ammonium Thiocyanate TS Conforms to USP 34

: USP Solution Potassium Carbonate TS Conforms to USP 34

: USP Solution Potassium Carbonate TS Conforms to USP 34

: USP Solution Potassium Permanganate 0.100 Normal ) Conforms to USP 34

: USP Solution Potassium Permanganate 0.100 Normal ) Conforms to USP 34

: European Pharmacopoeia Reagent Ammonium Carbonate Solution

: European Pharmacopoeia Reagent Iodoplatinate reagent

: European Pharmacopoeia Reagent Molybdovanadic reagent

: European Pharmacopoeia Reagent Naphtolbenzein Solution

: European Pharmacopoeia Reagent Potassium Permanganate Solution

: European Pharmacopoeia Reagent Potassium Pyroantimonate Solution

: European Pharmacopoeia Reagent Sodium Carbonate Solution

: European Pharmacopoeia Reagent Zinc chloride Solution iodinated

: European Pharmacopoeia Reagent 0.1M Ammonium thiocyanate

: European Pharmacopoeia Reagent 0.02M Potassium Permanganate

: European Pharmacopoeia Reagent Concentrated to make Sodium Standard sol (200ppm Na)

: Morphine-3-beta-D-glucuronide-D3,100ug/mL 于甲醇/0.5%NaOH

: Nalorphine HCl,1.0mg/mL as free base

: Fluconazole impurity B

: Fluconazole impurity C

: Mab Mix creatinine kinase isoenzyme MM

: MABM-INN22-IgG Human chorionic gonadotropin b-chain

: Creatine Kinase-MM Monoclonal Antibody (14.15)

: Creatine Kinase-MM Monoclonal Antibody (14.5)

: Creatine Kinase-MM Monoclonal Antibody (14.52)

: Wakopak Navi C18-5硅胶柱（235-60531）

: Wakopak Navi C18-5硅胶柱（231-60533）

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