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《自然医学》:一种可以显著延长乳腺癌患者生命的新药
在LMU大学医院乳房中心主任Nadia Harbeck教授的共同领导下,一个国际研究小组在临床试验中测试了一种新药曲妥珠单抗德鲁西替康。“效果很好,”肿瘤学家报告说。根据迄今为止的研究结果,生存时间大大增加。试验结果发表在《自然医学》杂志上。[查看]
http://cxbio.com/Article/20241010100_industrialnews_1.html
PNAS:有缺陷的DNA修复机制与亨廷顿氏病
麦克马斯特大学的研究人员发现,亨廷顿舞蹈症患者体内突变的蛋白质不能像预期的那样修复DNA,从而影响了脑细胞自愈的能力。这项研究于2024年9月27日发表在美国国家科学院院刊上,发现亨廷顿蛋白有助于产生对修复DNA损伤很重要的特殊分子。这些分子被称为Poly [ADP-ribose],聚集在受损的DNA周围,像一张网一样,吸引修复过程所需的所有因素。[查看]
http://cxbio.com/Article/pnasyqxddnaxfjzyhtds_1.html
N<font color='red'>AD</font>辅酶系列在IVD中的应用
在生化诊断中,NAD-NADH和NADP-NADPH显色系统是其重要的一部分。利用NAD/NADH和NADP/NADPH在340 nm 吸光值的差异,是许多酶活力水平检测的常见方法。西宝生物提供诊断级烟酰胺辅酶系列产品,包括NAD、NADH、NADP和NADPH等,详情致电400-021-8158![查看]
http://cxbio.com/Article/NADNADPNADHNADPH_1.html
2-脱氧葡萄糖(2DG)摄入检测试剂盒
2-脱氧葡萄糖(2DG)摄入检测试剂盒检测原理, 细胞摄入2DG后,经过细胞内生化酶的催化,通过检测产生的NADPH进行研究。[查看]
http://cxbio.com/Article/2DG_1.html
衰老的新秘密:细胞衰老有时并非坏事
桑福德伯纳姆普雷比和拉霍亚免疫学研究所的科学家们揭示了一个关于衰老的新秘密,衰老是一种类似于睡眠的细胞状态,更容易影响衰老细胞。Adams、Dasgupta和他们的合作者于2024年8月22日在《Molecular Cell》杂志上发表了研究结果,描述了衰老细胞引起的炎症和一种蛋白质之间的新联系,这种蛋白质参与了将六英尺长的DNA紧紧缠绕到细胞核中心的过程。[查看]
http://cxbio.com/Article/sldxmmxbslysbfhs_1.html
Science Advances:一种能量产生酶在治疗帕金森病中的作用
根据威尔康奈尔医学院的研究人员领导的一项临床前研究,一种名为PGK1的酶在脑细胞化学能的产生中起着意想不到的关键作用。研究人员发现,增强它的活性可能有助于大脑抵抗可能导致帕金森病的能量不足。这项研究发表在8月21日的《科学进展》杂志上[查看]
http://cxbio.com/Article/scienceadvancesyznlc_1.html
LBIS(R) 小鼠/大鼠 高分子量脂联素 ELISA 试剂盒
Adiponectin(脂联素)是脂肪细胞分泌的一种细胞因子。作为脂肪细胞因子,控制脂肪代谢和胰岛素感受性、是抗糖尿病、抗动脉粥样硬化、抗炎症的重要物质。Adiponectin 与各种各样的生长因子相结合有明显的亲和性,将其隔离能影响细胞的生长、血管新生和细胞组织的重建。LBIS(R) 的此款试剂盒只用于测定高分子 Adiponectin。[查看]
http://cxbio.com/Article/Adiponectin_ELISA_1.html
Science子刊:新治疗方法促进小鼠多能干细胞的产生
基因组调控中心(CRG)的研究人员发现了一种加速小鼠多能干细胞生产和质量的治疗方法。这一发现有可能改善具有两条X染色体的个体的疾病建模和药物测试;女性、变性男性或患有克氏综合征的额外X染色体的男性。研究结果发表在《Science Advances》杂志上[查看]
http://cxbio.com/Article/sciencezkxzlffcjxsdn_1.html
Nature子刊:两种调节线粒体自噬的蛋白质,开辟了一条新的途径
WEHI的研究人员与维也纳大学的一个团队合作,发现了两种调节线粒体自噬的蛋白质, NAP1和SINTBAD,它们参与调节细胞中有丝分裂的激活。[查看]
http://cxbio.com/Article/20240725_industrialnews_1.html
百日咳毒素(百日咳杆菌)
百日咳毒素由具有NAD +糖水解酶和ADP-核糖基转移酶活性的酶活性A原子亚基(S-1)和B寡聚体亚基(S-2,S-3,S-4和S-5)组成),其负责将天然毒素附着到真核细胞表面。百日咳毒素通过ADP核糖基化A亚基的羧基末端附近的半胱氨酸将来自受体的G蛋白解偶联。[查看]
http://cxbio.com/Article/PTX_1.html
《Nature Neuroscience》可增强神经胶质细胞的蛋白质
最近发表在《Nature Neuroscience》杂志上的一项研究表明,PLXNB1编码的Plexin-B1调节阿尔茨海默病(AD)斑块周围神经胶质网的激活。[查看]
http://cxbio.com/Article/natureneurosciencekz_1.html
蛋白质组学研究发现重症COVID-19的血浆标志物
近日,波士顿儿童医院、哈佛大学医学院等机构的研究人员在血浆中发现了一些蛋白标志物,可预测日益严重或致命的COVID-19。这项研究成果于5月24日发表在《Science Advances》杂志上。[查看]
http://cxbio.com/Article/dbzzxyjfxzzcovid19dx_1.html
Culture(R) A-83-01
Culture(R) A-83-01,是ALK4、ALK5、ALK7的选择性抑制剂。可以抑制Smad2/3的磷酸化和TGF-β诱导性的上披肩组织转换。本产品对骨形成因子typeI受体、p38MAP激酶、细胞外抑制激酶几乎没有影响。[查看]
http://cxbio.com/Article/CultureA-83-01_1.html
Cell子刊新研究揭示了线粒体蛋白在心脏再生中的关键作用
现在,一项新的研究探索了超复合体组装的机制,并揭示了线粒体组装因子对心脏再生的主要影响。这项研究是由国家心血管研究中心(CNIC)的jos Antonio Enríquez博士和Dra共同领导的。瑞士伯尔尼大学的Nadia Mercader是CNIC的访问科学家。这项发表在《发育细胞》上的研究表明,Cox7a蛋白家族的一员在CIV二聚体的组装中起着重要作用,这种组装对线粒体的正确功能至关重要,因此对细胞能量的产生至关重要。[查看]
http://cxbio.com/Article/20240515_INDUSTRIALNEWS_1.html
贻贝粘蛋白功能及应用场景
贻贝粘蛋白(Mussel Adhesive Protein,MAP)是一种由海洋贻贝足丝腺分泌的足丝蛋白,分子量约为100kDa,其结构中含有赖氨酸和多巴基团。该蛋白质在医学和化妆品行业中有着广泛的应用,特别是在皮肤护理和伤口愈合方面。[查看]
http://cxbio.com/Article/MusselAdhesiveProtein_1.html
记录总数:709 | 页数:48  <...32333435363738394041...>  
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β-Galactosidase, recombinant, EIA Grade,from E. coli overproducer, lyophilizate
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Peroxidase (POD), EIA Grade,from horseradish, lyophilizate
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Coenzyme A, Grade I,free acid
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FAD,disodium salt
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NAD, Grade I,free acid
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NADH, Grade I,disodium salt
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Analytical Grade Water
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Lead Acetate Solution (CH COO) Pb, 10%
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Adenosine Deaminase,from calf intestine, suspension
Adenosine Deaminase,from calf intestine, suspension
Glutamate Dehydrogenase (NAD(P)),from E.coli overproducer, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from E.coli overproducer, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, chemically modified, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, chemically modified, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, solution
Glutamate Dehydrogenase (NAD(P)),from beef liver, solution
D-乳酸脱氢酶(D-LDH), Grade I
D-乳酸脱氢酶(D-LDH), Grade I
D-乳酸脱氢酶(D-LDH), Grade II
D-乳酸脱氢酶(D-LDH), Grade II
NAD(P)H Dehydrogenase (quinone) (Diaphorase),from pig heart, suspension
NAD(P)H Dehydrogenase (quinone) (Diaphorase),from pig heart, suspension
Liberase MTF C/T, GMP Grade,sterile filtered, lyophilizate
Liberase MTF C/T, GMP Grade,sterile filtered, lyophilizate
Liberase T-Flex, Research Grade,sterile filtered, lyophilizate
Liberase T-Flex, Research Grade,sterile filtered, lyophilizate
Endoproteinase Asp-N, Sequencing Grade,from a mutant of Pseudomonas fragi, lyophilizate
Endoproteinase Asp-N, Sequencing Grade,from a mutant of Pseudomonas fragi, lyophilizate
Endoproteinase Glu-C, Sequencing Grade,from Staphylococcus aureus V8, lyophilizate
Endoproteinase Glu-C, Sequencing Grade,from Staphylococcus aureus V8, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution
Glucose Dehydrogenase (NAD Dependent)
Glucose Dehydrogenase (NAD Dependent)
Glucose Oxidase (GOD), Grade I,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade I,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade II,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade II,from Aspergillus niger overproducer, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Peroxidase (POD), Grade II,from horse radish, lyophilizate
Peroxidase (POD), Grade II,from horse radish, lyophilizate
DADK嗪草酮标准品
DADK嗪草酮标准品
1-cis-3-Chloroallyl-3,5,7-triaza-1-azonia-adamantane chloride
1-cis-3-Chloroallyl-3,5,7-triaza-1-azonia-adamantane chloride
Oxadiargyl
Oxadiargyl
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopeoia Lead Acetate Solution
European Pharmacopeoia Lead Acetate Solution
European Pharmacopoeia Reagent Molybdovanadic reagent
European Pharmacopoeia Reagent Molybdovanadic reagent
European Pharmacopoeia Reagent 0.1M Lead Nitrate
European Pharmacopoeia Reagent 0.1M Lead Nitrate
European Pharmacopoeia Reagent Concentrated to make Cadmium Standard sol. (0.1% Cd)
European Pharmacopoeia Reagent Concentrated to make Cadmium Standard sol. (0.1% Cd)
European Pharmacopoeia Lead Solution (0.1% Pb)
European Pharmacopoeia Lead Solution (0.1% Pb)
European Pharmacopoeia Reagent Concentrate to make Lead solution (100ppm Pb)
European Pharmacopoeia Reagent Concentrate to make Lead solution (100ppm Pb)
EDDP perchlorate (Methadone metabolite),100ug/mL (as pyrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),100ug/mL (as pyrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),1.0mg/mL (as pyrrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),1.0mg/mL (as pyrrolinium) 于甲醇
Loratadine impurity F
Loratadine impurity F
氧化铝 (Reduction Grade) 标准物质
氧化铝 (Reduction Grade) 标准物质
MAB<HCG>M-INN22-IgG Human chorionic gonadotropin b-chain
MABM-INN22-IgG Human chorionic gonadotropin b-chain